The first member of this drug class that was approved by the FDA to treat high cholesterol was lovastatin, back in the late 1980s (Endo, 2010). For High Cholesterol: This medicine did a number on my legs. for more info. If you have any medical questions or concerns, please talk to your healthcare provider. Less than 2% of people who take Lipitor have abnormal liver enzyme levels noted on liver function tests. So contrary to the hype about Lecithin, it did not work. It is clear, I cannot take statins of any kind. (n.d.). Rarely, serious side effects like muscle pain and breakdown may occur. Started on Crestor 9 years ago and couldn't stand the pain in my legs. These potentially life-saving medications have some important medical uses, but the downside is that they could also cause muscle pain or muscle cramps—also known as statin-induced muscle pain. My experience switching from Lipitor to Crestor was quite different. Endo, A. High cholesterol and elevated triglycerides are major risk factors for the development of heart disease. Like other statins, Crestor lowers total cholesterol, LDL cholesterol, and triglycerides while increasing HDL cholesterol. Because of this, you should have blood tests to check your liver before starting this medication (UpToDate, n.d.). Crestor rated 6.0/10 vs Lipitor rated 4.8/10 in overall patient satisfaction. And it affects my memory and motor skills. Crestor is made by AstraZeneca and is considered the most potent (strongest) statin. Statin medications act on a specific enzyme in the liver called hydroxymethylglutaryl-CoA (HMG-CoA) reductase. Crestor and Lipitor also specifically lower LDL (“bad cholesterol”), raise HDL (“good cholesterol”), and improve triglyceride levels (types of fat molecules in the bloodstream). Lot of stress for me and my family. View more. In fact, heart disease is the leading cause of death for men and women in the United States (CDC, 2020). Comparison of the efficacy and safety of rosuvastatin versus atorvastatin, simvastatin, and pravastatin across doses (STELLAR**STELLAR = Statin Therapies for Elevated Lipid Levels compared Across doses to Rosuvastatin. hydroxymethylglutaryl-CoA (HMG-CoA) reductase, https://www.cdc.gov/heartdisease/facts.htm#:~:text=Heart%20disease%20is%20the%20leading,1%20in%20every%204%20deaths, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3108295/, https://pubmed.ncbi.nlm.nih.gov/12860216/, https://jamanetwork.com/journals/jamacardiology/fullarticle/2583425, https://www.ncbi.nlm.nih.gov/books/NBK430940/, https://www.uptodate.com/contents/atorvastatin-drug-information?search=lipitor&topicRef=4564&source=see_link#F137632, https://www.uptodate.com/contents/rosuvastatin-drug-information. It is effective at reducing total cholesterol, LDL cholesterol, and triglycerides. The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. It is available in 10 mg, 20 mg, 40 mg, and 80 mg tablets that are typically taken once daily. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Statins are one of the most popular classes of prescription drugs. Data sources include IBM Watson Micromedex (updated 2 Nov 2020), Cerner Multum™ (updated 2 Nov 2020), ASHP (updated 23 Oct 2020) and others. Over 500 generic drugs, each $5 per month. Treasure Island (FL): StatPearls Publishing; 2020 Jan-. Crestor is more potent and causes a more significant lowering of total cholesterol, but Crestor and Lipitor similarly decrease the buildup of plaques in the blood vessels. A total of 183 drugs are known to interact with Crestor: A total of 309 drugs are known to interact with Lipitor: ** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. It is clear, I cannot take statins of any kind. I have red all your reviews below and I decided to lower the dose and take Crestor every other day and I will see If the pain will disappear or not and I will discuss that as well with my cardiologist. Both Crestor and Lipitor belong to a class of medications called statins. Rarely, people may have muscle breakdown (myopathy) that leads to liver damage and kidney failure (rhabdomyolysis). There may be variations in CSA schedules between individual states. A 30-day supply of Lipitor will cost you around $207 (without insurance), while generic atorvastatin is approximately $17–$19 for a month’s supply. Don't know what I will try next. I have red all your reviews below and I decided to lower the dose and take Crestor every other day and I will see If the pain will disappear or not and I will discuss that as well with my cardiologist. Both medications are relatively well-tolerated. Common side effects include muscle aches (myalgia), headache, dizziness, nausea, and constipation. Compare Crestor vs Lipitor head-to-head with other drugs for uses, ratings, cost, side effects and interactions. Please review our In the end, you should consult your healthcare provider to determine which one is right for you. Crestor is the brand name for rosuvastatin, and Lipitor is the brand name for atorvastatin. It got the numbers down, but I had 3 ER visits in one week and spent the night in the hospital because my legs were acting up and it scared me and my heart did weird things. hemorrhagic stroke, arthralgia, diarrhea, and nasopharyngitis. Myositis presents itself with muscle pain, tenderness, or weakness and a higher level of creatine kinase in the bloodstream. Despite this, there was no significant difference between the two drugs in how well they decreased the volume of atherosclerotic buildup in the arteries. Side effects of Crestor that are different from Lipitor include nausea , vomiting , muscle pain , … View all Common side effects include: The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. They might have a similar mechanism of action but there are some differences, which must be pointed out.
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